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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image15 June 2026 Vol. No. 15 ; Issue No.739
Publications

1. Maniar J, Dhas P, Datt P, Dange P, Gandhi KA, Bhatia D, Chaubal R, Gardi N, Kembhavi Y, Joshi S, Badwe R, Gupta S. Hypoxia-reoxygenation cycle leads to context dependent phenotypic effects in breast cancer cell lines. Molecular Biology Reports.;53(1):931.

2. Sharma A, Garale M, Lila A, Chakrabarty N, Badhe P, Patil V, Thakkar H, Memon S, Pantvaidya G, Bal M, Barnabas R, Karlekar M, Pai T, Sathe P, Fernandes G, Bandgar T (2026). Diagnostic Performance of Parathyroid CT and CT-Guided Targeted Parathyroidectomy in MEN1-Associated Primary Hyperparathyroidism, Annals of Endocrinology.

3. Shivshankar S, Mhamane S, Patil PS, Deodhar K, Budukh AM (2026). The changing landscape of gastrointestinal cancers in India: An analysis involving published data from Cancer Incidence in Five Continents of 2013-2017 compared to 1988-1992. Indian Journal of Gastroenterology.

4. Redhu AK, Gadewal N, Gota V (2026). Targeting IDH1 (R132H)-Driven Oncometabolic Vulnerabilities: Structure-Guided Discovery of Phytochemical Inhibitor. In Silico Research in Biomedicine

5. Raveendran V, Sinha S, Mukherjee P, Kumar A, Shinde PH, Prabu AC, Punde RN, Chaudhari LN, Mathew SM, Mohanty S, Swain M, Budrukkar A, Ghosh Laskar S(2026) Exploring the need for plan adaptation in robustly optimized head and neck intensity modulated proton therapy: A dosimetric perspective from initial institutional experience. Clinical Oncology.

Patent
ACTREC (2026). An Electrosurgical Instrument for En-Bloc Resection of Bladder Tumors. Design Number:496072-001.The Patent Office Government of India.

Site of the Week

The Genome Aggregation Database (gnomAD) is the result of a coalition of investigators willing to share aggregate exome and genome sequencing data from a variety of large-scale sequencing projects, and make summary data available for the wider scientific community.

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Interesting Reads

Menendez-Montes I, Marin-Vicente C, Mukherjee S, Ahmed MS, Gomez MJ, Anene-Nzelu CG, Lee CJM, Koslowski S, Solmonson A, Tassin T, Ali SR, Pessoa P, Elnwasany A, Lam NT, Thet S, Calvo E, Cardoso AC, Pereira AHM, Xiao F, Wang P, Mohamed A, El-Feky H, Elghamry A, Gancedo-Alonso G, Nguyen NUN, Hsu CC, Westfall AK, DeBerardinis R, Foo RS, Kinter M, Pressé S, Xing C, Szweda L, Aroumougame A, Sanchez-Cabo F, Enriquez JA, Torres M, Vazquez J, Sadek HA (2026). Mitochondria directly interact with the nuclear pore complex. Nature.

Video of the Week
Immunotherapy for Lynch Syndrome Associated Cancers
Upcoming Events
Workshop on Estimands and Sensitivity Analysis in Clinical Research

June 26-27, 2026

At ACTREC, Tata Memorial Centre, Kharghar

Biomarker Applications to Inform Cancer Prevention

June 25-27, 2026,

Online Workshop, by ACTREC, Tata Memorial Centre

A workshop on Basics of NGS Data Analysis

June 24-25, 2026

At ACTREC, Kharghar, Navi Mumbai

Do You Know?

In 1997, FDA approved Rituxan (rituximab), the first monoclonal antibody, to treat non-Hodgkin’s lymphoma.

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Cancer News
UCLA-led research suggests early heart changes may predict future cancer risk.

Eurekalert, 11/06/2026

The researchers assessed baseline cardiac structure and function using cardiac MRI imaging at enrollment and participants were followed for cancer incidence over an average of 18 years. They also used multivariable statistical models to investigate the association of cardiac MRI measurements...

First CD123-targeted ADC secures FDA approval for rare blood cancer

Nature, 11/06/2026

The FDA approved pivekimab sunirine in this setting on the basis of a phase I/II trial of the ADC in 84 adults with frontline or relapsed/refractory BPDCN. In 33 patients with treatment-naive BPDCN, 23 (70%) achieved a complete response or clinical complete remission (CR/CRc),....

Scientists shut down cancer DNA repair to overcome drug resistance

Sciencedaily, 10/06/2026

Cancer cells often survive treatment by fixing the DNA damage that therapy is meant to cause. Researchers found that UNI418 can disrupt this repair ability, leaving cancer cells more exposed. When combined with a PARP inhibitor, it helped resistant cancer cells respond to treatment again...

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